As an essential element of cell membranes, phosphatidylserine is thought to have a key role in maintaining your memory sharp as you get older. (Studies in animals suggest that levels decline with age.)
Phosphatidylserine is a fatty substance manufactured in the body that covers and guards nerve cells (especially within the brain) and helps transmits messages between them.
Phosphatidylserine is found naturally in certain foods and is also sold in a dietary supplement.
Uses for Phosphatidylserine
Phosphatidylserine supplements are promoted as a natural remedy for a variety of health conditions, including:- Depression
- Stress
- Attention deficit-hyperactivity disorder (ADHD)
- Alzheimer's disease
- Anxiety
- Multiple sclerosis
In addition, phosphatidylserine containing supplements are indicated to promote healthy sleep, preserve memory, enhance exercise performance, and improve mood.
The Benefits of Phosphatidylserine
1) Exercise Capacity and Muscle Soreness
Phosphatidylserine supplements do help boost exercise capacity and improve athletic performance, according to a 2006 article announced in Sports Medicine. In their analysis of the available research on the use of phosphatidylserine supplements among individuals who exercised, the report's authors also found that phosphatidylserine does help decrease muscle soreness and protect against the increase in levels of cortisol (a stress hormone) that often occurs as a result of overtraining.
2) Depression
In a 2015 study published in Mental Illness, for instance, people over the age of 65 with major depression took a supplement containing phosphatidylserine and the omega-3 fatty acids DHA and EPA three times daily for 12 weeks. Phosphatidylserine is thought to play a role in helping to regulate mood. At the study's end, scores on a depression scale had improved. More research is needed from large-scale, well-designed clinical studies before phosphatidylserine can be recommended.
3) ADHD
A study performed to 200 children with ADHD were assigned to 15 weeks of treatment with either a placebo or a supplement containing phosphatidylserine and omega-3 fatty acids. Using phosphatidylserine in combination with omega-3 fatty acids may aid in the treatment of ADHD in children, suggests a 2012 study published in European Psychiatry.
Study results revealed that participants treated with the combination of phosphatidylserine and omega-3 fatty acids experienced a significantly greater reduction in hyperactive/impulsive behavior and a greater improvement in mood (compared to those given the placebo).
4) Memory
In a 2010 study published in the Journal of Clinical Biochemistry and Nutrition, 78 elderly people with mild cognitive impairment were assigned to six months of treatment with phosphatidylserine supplements, or a placebo. Phosphatidylserine is often taken to try to slow age-related memory loss. In tests performed at the end of the six-month period, participants with relatively low memory scores at the start of the study were found to have felt a significant improvement in memory.
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